Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae

BACKGROUND: The development of novel yeast strains with increased tolerance toward inhibitors in lignocellulosic hydrolysates is highly desirable for the production of bio-ethanol. Weak organic acids such as acetic and formic acids are necessarily released during the pretreatment (i.e. solubilizatio...

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Main Authors: Hasunuma, Tomohisa, Sanda, Tomoya, Yamada, Ryosuke, Yoshimura, Kazuya, Ishii, Jun, Kondo, Akihiko
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025834/
https://ncbi.nlm.nih.gov/pubmed/21219616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-2
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