Cathepsin B facilitates Autophagy mediated apoptosis in SPARC Overexpressed Primitive Neuroectodermal Tumor cells

Medulloblastoma and neuroblastoma belong to a group of neoplasms designated as primitive neuroectodermal tumors (PNETs). Secreted Protein, Acidic and Rich in Cysteine (SPARC) is a matrix-associated glycoprotein that influences a variety of cellular activities in vitro and in vivo. Here, we provide e...

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Hauptverfasser: Bhoopathi, Praveen, Chetty, Chandramu, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S., Lakka, Sajani
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025815/
https://ncbi.nlm.nih.gov/pubmed/20339379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.28
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