Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations

Genome-wide association studies (GWAS) have identified common variants associated with breast cancer risk among women of European and Asian ancestries. To assess the generalizability across ethnic/racial populations of a risk score derived from genotyping 12 highly replicated breast cancer GWAS hits...

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Autors principals: Chen, Fang, Stram, Daniel O, Le Marchand, Loïc, Monroe, Kristine R, Kolonel, Laurence N, Henderson, Brian E, Haiman, Christopher A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025800/
https://ncbi.nlm.nih.gov/pubmed/21102626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.185
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