Self-reported Ethnicity, Genetic Structure and the Impact of Population Stratification in a Multiethnic Study

It is well-known that population substructure may lead to confounding in case-control association studies. Here, we examined genetic structure in a large racially and ethnically diverse sample consisting of 5 ethnic groups of the Multiethnic Cohort study (African Americans, Japanese Americans, Latin...

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Main Authors: Wang, Hansong, Haiman, Christopher A., Kolonel, Laurence N., Henderson, Brian E., Wilkens, Lynne R., Le Marchand, Loïc, Stram, Daniel O.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057055/
https://ncbi.nlm.nih.gov/pubmed/20499252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0841-4
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