mRNA degradation controls differentiation state-dependent differences in transcript and splice variant abundance

Expression profiling experiments usually provide a static snapshot of messenger RNA (mRNA) levels. Improved understanding of the dynamics of mRNA synthesis and degradation will aid the development of sound bioinformatic models for control of gene expression. We studied mRNA stability in proliferatin...

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Dettagli Bibliografici
Autori principali: 't Hoen, Peter A. C., Hirsch, Michael, de Meijer, Emile J., de Menezes, Renée X., van Ommen, Gert Jan, den Dunnen, Johan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025562/
https://ncbi.nlm.nih.gov/pubmed/20852259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq790
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