mRNA degradation controls differentiation state-dependent differences in transcript and splice variant abundance

Expression profiling experiments usually provide a static snapshot of messenger RNA (mRNA) levels. Improved understanding of the dynamics of mRNA synthesis and degradation will aid the development of sound bioinformatic models for control of gene expression. We studied mRNA stability in proliferatin...

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Detalhes bibliográficos
Main Authors: 't Hoen, Peter A. C., Hirsch, Michael, de Meijer, Emile J., de Menezes, Renée X., van Ommen, Gert Jan, den Dunnen, Johan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025562/
https://ncbi.nlm.nih.gov/pubmed/20852259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq790
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