mRNA degradation controls differentiation state-dependent differences in transcript and splice variant abundance

Expression profiling experiments usually provide a static snapshot of messenger RNA (mRNA) levels. Improved understanding of the dynamics of mRNA synthesis and degradation will aid the development of sound bioinformatic models for control of gene expression. We studied mRNA stability in proliferatin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: 't Hoen, Peter A. C., Hirsch, Michael, de Meijer, Emile J., de Menezes, Renée X., van Ommen, Gert Jan, den Dunnen, Johan T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025562/
https://ncbi.nlm.nih.gov/pubmed/20852259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq790
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