Cargando...

p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

The tumor suppressor p53 is a central regulator of cell-cycle arrest and apoptosis by acting as a transcription factor to regulate numerous genes. We identified all human p53-regulated mRNAs by microarray analyses and searched for protein-coding genes which contain intronic miRNAs. Among others, thi...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Böhlig, Levin, Friedrich, Maik, Engeland, Kurt
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025554/
https://ncbi.nlm.nih.gov/pubmed/20833636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq796
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!