Retinoblastoma/p107/p130 Pocket Proteins: PROTEIN DYNAMICS AND INTERACTIONS WITH TARGET GENE PROMOTERS

The retinoblastoma (RB) tumor suppressor and its family members, p107 and p130, function by repressing E2F transcription factor activity to limit the expression of genes required for cell cycle progression. Traditionally, it is thought that the RB family proteins repress E2F target gene expression t...

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Bibliographic Details
Main Authors: Stengel, Kristy R., Thangavel, Chellappagounder, Solomon, David A., Angus, Steve P., Zheng, Yi, Knudsen, Erik S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740551/
https://ncbi.nlm.nih.gov/pubmed/19279001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808740200
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