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Chronic stress targets posttranscriptional mechanisms to rapidly upregulate α(1C)-subunit of Ca(v)1.2b calcium channels in colonic smooth muscle cells

Chronic stress elevates plasma norepinephrine, which enhances expression of the α(1C)-subunit of Ca(v)1.2b channels in colonic smooth muscle cells within 1 h. Transcriptional upregulation usually does not explain such rapid protein synthesis. We investigated whether chronic stress-induced release of...

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Main Authors: Li, Qingjie, Sarna, Sushil K.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025508/
https://ncbi.nlm.nih.gov/pubmed/21051529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00393.2010
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