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Phosphorylation of RalB is important for bladder cancer cell growth and metastasis
RalA and RalB are monomeric G proteins that are 83% identical in amino acid sequence, but have paralog-specific effects on cell proliferation, metastasis and apoptosis. Using in vitro kinase assays and phosphosite specific antibodies, here we show phosphorylation of RalB by protein kinase C (PKC) an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025490/ https://ncbi.nlm.nih.gov/pubmed/20940393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0952 |
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