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MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner
Apoptosis has an important role during development to regulate cell number. In differentiated cells, however, activation of autophagy has a critical role by enabling cells to remain functional following stress. In this study, we show that the antiapoptotic BCL-2 homologue MCL-1 has a key role in con...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025469/ https://ncbi.nlm.nih.gov/pubmed/21139567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.327 |
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