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Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter

To test the feasibility of using the survivin promoter to induce specific expression of sodium/iodide symporter (NIS) in cancer cell lines and tumors for targeted use of radionuclide therapy, a recombinant adenovirus, Ad-SUR-NIS, that expressed the NIS gene under control of the survivin promoter was...

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Autori principali: Huang, R, Zhao, Z, Ma, X, Li, S, Gong, R, Kuang, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025317/
https://ncbi.nlm.nih.gov/pubmed/21037556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.66
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