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Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter

To test the feasibility of using the survivin promoter to induce specific expression of sodium/iodide symporter (NIS) in cancer cell lines and tumors for targeted use of radionuclide therapy, a recombinant adenovirus, Ad-SUR-NIS, that expressed the NIS gene under control of the survivin promoter was...

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Bibliographic Details
Main Authors: Huang, R, Zhao, Z, Ma, X, Li, S, Gong, R, Kuang, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025317/
https://ncbi.nlm.nih.gov/pubmed/21037556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.66
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