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Modeling Sjögren’s Syndrome with Id3 Conditional Knockout Mice

The Id3 gene has been shown to play important roles in the development and function of broad tissue types including B and T cells. Id3 deficient mice develop autoimmune disease similar to human Sjögren’s syndrome. Both B and T lymphocytes have been implicated to contribute to the disease phenotype i...

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Detalhes bibliográficos
Main Authors: Guo, Zengli, Li, Hongmei, Han, Min, Xu, Tian, Wu, Xiaohui, Zhuang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025308/
https://ncbi.nlm.nih.gov/pubmed/20932862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2010.09.009
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