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Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression
It has been difficult to reconcile the absence of pathology and apparently normal behavior of mice lacking prion protein (PrP), referred to as Prnp(0/0) mice, with a mechanism of prion pathogenesis involving progressive loss of PrP(C)-mediated neuroprotection. However, here we report that Prnp(0/0)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025296/ https://ncbi.nlm.nih.gov/pubmed/17531449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2007.04.004 |
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