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Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers

The adaptive immune CRISPR/Cas and CRISPR/Cmr systems of the crenarchaeal thermoacidophile Sulfolobus were challenged by a variety of viral and plasmid genes, and protospacers preceded by different dinucleotide motifs. The genes and protospacers were constructed to carry sequences matching individua...

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Hlavní autoři: Gudbergsdottir, Soley, Deng, Ling, Chen, Zhengjun, Jensen, Jaide V K, Jensen, Linda R, She, Qunxin, Garrett, Roger A
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025118/
https://ncbi.nlm.nih.gov/pubmed/21166892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07452.x
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