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Computational Design of Auxotrophy-Dependent Microbial Biosensors for Combinatorial Metabolic Engineering Experiments

Combinatorial approaches in metabolic engineering work by generating genetic diversity in a microbial population followed by screening for strains with improved phenotypes. One of the most common goals in this field is the generation of a high rate chemical producing strain. A major hurdle with this...

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Detalhes bibliográficos
Main Authors: Tepper, Naama, Shlomi, Tomer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025009/
https://ncbi.nlm.nih.gov/pubmed/21283695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016274
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