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N-Acetyl-d-glucosaminylphosphatidylinositol De-N-acetylase from Entamoeba histolytica: METAL ALTERS CATALYTIC RATES BUT NOT SUBSTRATE AFFINITY
PIG-L/GPI12 proteins are endoplasmic reticulum-resident membrane proteins involved in the second step of glycosylphosphatidylinositol anchor biosynthesis in eukaryotes. We show that the Entamoeba histolytica PIG-L protein is optimally active in the acidic pH range. The enzyme has an intrinsic low le...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024749/ https://ncbi.nlm.nih.gov/pubmed/21118807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.178343 |
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