N-Acetyl-d-glucosaminylphosphatidylinositol De-N-acetylase from Entamoeba histolytica: METAL ALTERS CATALYTIC RATES BUT NOT SUBSTRATE AFFINITY

PIG-L/GPI12 proteins are endoplasmic reticulum-resident membrane proteins involved in the second step of glycosylphosphatidylinositol anchor biosynthesis in eukaryotes. We show that the Entamoeba histolytica PIG-L protein is optimally active in the acidic pH range. The enzyme has an intrinsic low le...

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Detalhes bibliográficos
Main Authors: Ashraf, Mohammad, Yadav, Bhawna, Perinthottathil, Sreejith, Kumar, Kokila Sree, Vats, Divya, Muthuswami, Rohini, Komath, Sneha Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024749/
https://ncbi.nlm.nih.gov/pubmed/21118807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.178343
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