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Biochemical Characterization of Bacteriophage T4 Mre11-Rad50 Complex

The Mre11-Rad50 complex (MR) from bacteriophage T4 (gp46/47) is involved in the processing of DNA double-strand breaks. Here, we describe the activities of the T4 MR complex and its modulation by proteins involved in homologous recombination. T4 Mre11 is a Rad50- and Mn(2+)-dependent dsDNA exonuclea...

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Main Authors: Herdendorf, Timothy J., Albrecht, Dustin W., Benkovic, Stephen J., Nelson, Scott W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024732/
https://ncbi.nlm.nih.gov/pubmed/21081488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178871
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