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Superior antitumor response induced by large stress protein chaperoned protein antigen compared with peptide antigen

Our previous studies have demonstrated that the natural chaperone complexes of full-length tumor protein antigens (e.g., gp100) and large stress proteins (e.g., hsp110 and grp170) with exceptional antigen holding capabilities augment potent tumor protective immunity. Here we assess the peptide-inter...

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Détails bibliographiques
Auteurs principaux: Wang, Xiang-Yang, Sun, Xiaolei, Chen, Xing, Facciponte, John, Repasky, Elizabeth, Kane, John, Subjeck, John
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024709/
https://ncbi.nlm.nih.gov/pubmed/20439916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903891
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