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Covalent Crosslinking of Tumor Antigens Stimulates an Antitumor Immune Response
In murine renal cell carcinoma and melanoma models, vaccination with crosslinked tumor antigen in the absence of other adjuvants inhibited the growth of RENCA and B16 tumors. Vaccination with crosslinked antigens (CA9 or gp100) enhanced the cellular immune response as measured by ELISPOT and cytotox...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941738/ https://ncbi.nlm.nih.gov/pubmed/20682362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.07.060 |
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