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CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells
CD22 is a member of the sialic acid-binding Ig-like lectin (Siglec) family that is known to be a regulator of B cell signaling. Its B cell-specific expression makes it an attractive target for immunotoxin-mediated B cell depletion therapy for the treatment of B cell lymphomas and autoimmune diseases...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024466/ https://ncbi.nlm.nih.gov/pubmed/21178016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003005 |
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