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Influence of ApoA-I Domain Structure on Macrophage Reverse Cholesterol Transport in Mice
OBJECTIVE: To determine the influence of apoA-I tertiary structure domain properties on the anti-atherogenic properties of the protein. Two chimeric hybrids with the N-terminal domains swapped (human-M apoA-I and mouse-H apoA-I) were expressed in apoA-I-null mice with adeno-associated virus (AAV) an...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024460/ https://ncbi.nlm.nih.gov/pubmed/21071688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.216226 |
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