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Aging-related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression

Age is the greatest risk factor for the development of epithelial cancers. In this minireview, we will examine key extracellular matrix and matricellular components, their changes with aging, and discuss how these alterations might influence the subsequent progression of cancer in the aged host. Bec...

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Détails bibliographiques
Auteurs principaux: Sprenger, Cynthia C., Plymate, Stephen R., Reed, May J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024458/
https://ncbi.nlm.nih.gov/pubmed/21351253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25615
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