Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR1

BACKGROUND: The cellular and molecular mechanisms of tumour response following chemotherapy are largely unknown. We found that low dose anti-tumour agents up-regulate early growth response 1 (EGR1) expression. EGR1 is a member of the immediate-early gene group of transcription factors which modulate...

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Główni autorzy: Matsunoshita, Yukihiro, Ijiri, Kosei, Ishidou, Yasuhiro, Nagano, Satoshi, Yamamoto, Takuya, Nagao, Hiroko, Komiya, Setsuro, Setoguchi, Takao
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2011
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024416/
https://ncbi.nlm.nih.gov/pubmed/21283769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016234
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