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Fine Mapping of the NRG1 Hirschsprung's Disease Locus
The primary pathology of Hirschsprung's disease (HSCR, colon aganglionosis) is the absence of ganglia in variable lengths of the hindgut, resulting in functional obstruction. HSCR is attributed to a failure of migration of the enteric ganglion precursors along the developing gut. RET is a key r...
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Main Authors: | , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024406/ https://ncbi.nlm.nih.gov/pubmed/21283760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016181 |
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