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A Computational and Experimental Study of the Regulatory Mechanisms of the Complement System

The complement system is key to innate immunity and its activation is necessary for the clearance of bacteria and apoptotic cells. However, insufficient or excessive complement activation will lead to immune-related diseases. It is so far unknown how the complement activity is up- or down- regulated...

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Autori principali: Liu, Bing, Zhang, Jing, Tan, Pei Yi, Hsu, David, Blom, Anna M., Leong, Benjamin, Sethi, Sunil, Ho, Bow, Ding, Jeak Ling, Thiagarajan, P. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024260/
https://ncbi.nlm.nih.gov/pubmed/21283780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001059
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