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Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy

Loss-of-function mutations in dysferlin cause muscular dystrophy, and dysferlin has been implicated in resealing membrane disruption in myofibers. Given the importance of membrane fusion in many aspects of muscle function, we studied the role of dysferlin in muscle growth. We found that dysferlin nu...

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Detalhes bibliográficos
Main Authors: Demonbreun, Alexis R., Fahrenbach, John P., Deveaux, Kieran, Earley, Judy U., Pytel, Peter, McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024047/
https://ncbi.nlm.nih.gov/pubmed/21127009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq522
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