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Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport
Amyloid-β (Aβ) peptides, derived from the amyloid precursor protein, and the microtubule-associated protein tau are key pathogenic factors in Alzheimer’s disease (AD). How exactly they impair cognitive functions is unknown. Here we assessed the effects of Aβ and tau on axonal transport of mitochondr...
Sparad:
| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024010/ https://ncbi.nlm.nih.gov/pubmed/20829454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194653 |
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