Llwytho...

Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport

Amyloid-β (Aβ) peptides, derived from the amyloid precursor protein, and the microtubule-associated protein tau are key pathogenic factors in Alzheimer’s disease (AD). How exactly they impair cognitive functions is unknown. Here we assessed the effects of Aβ and tau on axonal transport of mitochondr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vossel, Keith A., Zhang, Kai, Brodbeck, Jens, Daub, Aaron C., Sharma, Punita, Finkbeiner, Steven, Cui, Bianxiao, Mucke, Lennart
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024010/
https://ncbi.nlm.nih.gov/pubmed/20829454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194653
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