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Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C

Inhibition of gap junctional intercellular communication (GJIC) and the activation of intracellular mitogenic pathways are common hallmarks of epithelial derived cancer cells. We previously determined that the 1-methyl and not the 2-methyl isomer of anthracene, which are prominent cigarette smoke co...

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Detalhes bibliográficos
Main Authors: Upham, Brad L., Bláha, Ludek, Babica, Pavel, Park, Joon-Suk, Sovadinova, Iva, Pudrith, Charles, Rummel, Alisa M., Weis, Liliane M., Sai, Kimie, Tithof, Patti K., Gužvić, Miodrag, Vondráček, Jan, Machala, Miroslav, Trosko, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023995/
https://ncbi.nlm.nih.gov/pubmed/18377422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2008.00752.x
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