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PKA and PKC are required for long-term but not short-term in vivo operant memory in Aplysia

We investigated the involvement of PKA and PKC signaling in a negatively reinforced operant learning paradigm in Aplysia, learning that food is inedible (LFI). In vivo injection of PKA or PKC inhibitors blocked long-term LFI memory formation. Moreover, a persistent phase of PKA activity, although no...

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Bibliographische Detailangaben
Hauptverfasser: Michel, Maximilian, Green, Charity L., Lyons, Lisa C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023968/
https://ncbi.nlm.nih.gov/pubmed/21169419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2026311
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