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Stepwise Release of Biologically Active HMGB1 during HSV-2 Infection

BACKGROUND: High mobility group box 1 protein (HMGB1) is a major endogenous danger signal that triggers inflammation and immunity during septic and aseptic stresses. HMGB1 recently emerged as a key soluble factor in the pathogenesis of various infectious diseases, but nothing is known of its behavio...

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Autores principales: Borde, Chloé, Barnay-Verdier, Stéphanie, Gaillard, Claire, Hocini, Hakim, Maréchal, Vincent, Gozlan, Joël
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023802/
https://ncbi.nlm.nih.gov/pubmed/21283827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016145
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