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CAG Repeats Determine Brain Atrophy in Spinocerebellar Ataxia 17: A VBM Study

BACKGROUND: Abnormal repeat length has been associated with an earlier age of onset and more severe disease progression in the rare neurodegenerative disorder spinocerebellar ataxia 17 (SCA17). METHODOLOGY/PRINCIPAL FINDINGS: To determine whether specific structural brain degeneration and rate of di...

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Hlavní autoři: Reetz, Kathrin, Kleiman, Alexandra, Klein, Christine, Lencer, Rebekka, Zuehlke, Christine, Brockmann, Kathrin, Rolfs, Arndt, Binkofski, Ferdinand
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023761/
https://ncbi.nlm.nih.gov/pubmed/21311576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015125
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