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CAG Repeats Determine Brain Atrophy in Spinocerebellar Ataxia 17: A VBM Study

BACKGROUND: Abnormal repeat length has been associated with an earlier age of onset and more severe disease progression in the rare neurodegenerative disorder spinocerebellar ataxia 17 (SCA17). METHODOLOGY/PRINCIPAL FINDINGS: To determine whether specific structural brain degeneration and rate of di...

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Detalhes bibliográficos
Main Authors: Reetz, Kathrin, Kleiman, Alexandra, Klein, Christine, Lencer, Rebekka, Zuehlke, Christine, Brockmann, Kathrin, Rolfs, Arndt, Binkofski, Ferdinand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023761/
https://ncbi.nlm.nih.gov/pubmed/21311576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015125
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