Transient Alteration of Cellular Redox Buffering before Irradiation Triggers Apoptosis in Head and Neck Carcinoma Stem and Non-Stem Cells

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is an aggressive and recurrent malignancy owing to intrinsic radioresistance and lack of induction of apoptosis. The major focus of this work was to design a transient glutathione depleting strategy during the course of irradiation of HNSCC i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Boivin, Anthony, Hanot, Maité, Malesys, Céline, Maalouf, Mira, Rousson, Robert, Rodriguez-Lafrasse, Claire, Ardail, Dominique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023721/
https://ncbi.nlm.nih.gov/pubmed/21283807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014558
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