Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes

Growth hormone (GH) inhibits fat accumulation and promotes protein accretion, therefore the fall in GH observed with weight gain and normal aging may contribute to metabolic dysfunction. To directly test this hypothesis a novel mouse model of adult onset-isolated GH deficiency (AOiGHD) was generated...

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Detalhes bibliográficos
Main Authors: Luque, Raul M., Lin, Qing, Córdoba-Chacón, José, Subbaiah, Papasani V., Buch, Thorsten, Waisman, Ari, Vankelecom, Hugo, Kineman, Rhonda D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023710/
https://ncbi.nlm.nih.gov/pubmed/21283519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015767
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