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Galactose-extended glycans of antibodies produced by transgenic plants

Plant-specific N-glycosylation can represent an important limitation for the use of recombinant glycoproteins of mammalian origin produced by transgenic plants. Comparison of plant and mammalian N-glycan biosynthesis indicates that β1,4-galactosyltransferase is the most important enzyme that is miss...

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Detalhes bibliográficos
Main Authors: Bakker, Hans, Bardor, Muriel, Molthoff, Jos W., Gomord, Véronique, Elbers, Ingrid, Stevens, Lucas H., Jordi, Wilco, Lommen, Arjen, Faye, Loïc, Lerouge, Patrice, Bosch, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30237/
https://ncbi.nlm.nih.gov/pubmed/11226338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031419998
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