Galactose-extended glycans of antibodies produced by transgenic plants

Plant-specific N-glycosylation can represent an important limitation for the use of recombinant glycoproteins of mammalian origin produced by transgenic plants. Comparison of plant and mammalian N-glycan biosynthesis indicates that β1,4-galactosyltransferase is the most important enzyme that is miss...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bakker, Hans, Bardor, Muriel, Molthoff, Jos W., Gomord, Véronique, Elbers, Ingrid, Stevens, Lucas H., Jordi, Wilco, Lommen, Arjen, Faye, Loïc, Lerouge, Patrice, Bosch, Dirk
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031419998
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