Galactose-extended glycans of antibodies produced by transgenic plants

Plant-specific N-glycosylation can represent an important limitation for the use of recombinant glycoproteins of mammalian origin produced by transgenic plants. Comparison of plant and mammalian N-glycan biosynthesis indicates that β1,4-galactosyltransferase is the most important enzyme that is miss...

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Autors principals: Bakker, Hans, Bardor, Muriel, Molthoff, Jos W., Gomord, Véronique, Elbers, Ingrid, Stevens, Lucas H., Jordi, Wilco, Lommen, Arjen, Faye, Loïc, Lerouge, Patrice, Bosch, Dirk
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC30237/
https://ncbi.nlm.nih.gov/pubmed/11226338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031419998
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