Altered Immune Response in Mice Deficient for the G Protein-coupled Receptor GPR34

The X-chromosomal GPR34 gene encodes an orphan G(i) protein-coupled receptor that is highly conserved among vertebrates. To evaluate the physiological relevance of GPR34, we generated a GPR34-deficient mouse line. GPR34-deficient mice were vital, reproduced normally, and showed no gross abnormalitie...

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Hauptverfasser: Liebscher, Ines, Müller, Uwe, Teupser, Daniel, Engemaier, Eva, Engel, Kathrin M. Y., Ritscher, Lars, Thor, Doreen, Sangkuhl, Katrin, Ricken, Albert, Wurm, Antje, Piehler, Daniel, Schmutzler, Sandra, Fuhrmann, Herbert, Albert, Frank W., Reichenbach, Andreas, Thiery, Joachim, Schöneberg, Torsten, Schulz, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023507/
https://ncbi.nlm.nih.gov/pubmed/21097509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196659
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