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Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor

Dysfunction of the melanocortin system can result in severe obesity accompanied with dyslipidemia and symptoms of the metabolic syndrome but the effect on vascular atherogenesis is not known. To study the impact of obesity and dyslipidemia on the cardiovascular system, we generated mice double-defic...

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發表在:PLoS One
Main Authors: Lede, Vera, Franke, Christin, Meusel, Andrej, Teupser, Daniel, Ricken, Albert, Thiery, Joachim, Schiller, Jürgen, Huster, Daniel, Schöneberg, Torsten, Schulz, Angela
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193345/
https://ncbi.nlm.nih.gov/pubmed/28030540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167888
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