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Engineered Annexin A5 Variants Have Impaired Cell Entry for Molecular Imaging of Apoptosis Using Pretargeting Strategies

Phosphatidylserine (PS) on apoptotic cells is a target for diagnosis and therapy using annexin A5 (anxA5). Pretargeting is a strategy developed to improve signal to background ratio for molecular imaging and to minimize undesired side effects of pharmacological and radiotherapy. Pretargeting relies...

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Detalhes bibliográficos
Main Authors: Ungethüm, Lisette, Kenis, Heidi, Nicolaes, Gerry A., Autin, Ludovic, Stoilova-McPhie, Svetla, Reutelingsperger, Chris P. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023486/
https://ncbi.nlm.nih.gov/pubmed/21078669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163527
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