The Actin-binding Protein, Actinin Alpha 4 (ACTN4), Is a Nuclear Receptor Coactivator that Promotes Proliferation of MCF-7 Breast Cancer Cells

Alpha actinins (ACTNs) are known for their ability to modulate cytoskeletal organization and cell motility by cross-linking actin filaments. We show here that ACTN4 harbors a functional LXXLL receptor interaction motif, interacts with nuclear receptors in vitro and in mammalian cells, and potently a...

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Bibliografiske detaljer
Main Authors: Khurana, Simran, Chakraborty, Sharmistha, Cheng, Xiwen, Su, Yu-Ting, Kao, Hung-Ying
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023480/
https://ncbi.nlm.nih.gov/pubmed/21078666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162107
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