The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720

FTY720 is a novel immunomodulating drug that can be phosphorylated inside cells; its phosphorylated form, FTY720-P, binds to a sphingosine 1-phosphate (S1P) receptor, S1P(1), and inhibits lymphocyte egress into the circulating blood. Although the importance of its pharmacological action has been wel...

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Detaylı Bibliyografya
Asıl Yazarlar: Hisano久, Yu, 野悠, Kobayashi小, Naoki, 林直木, Kawahara川, Atsuo, 原敦雄, Yamaguchi山, Akihito, 口明人, Nishi西, Tsuyoshi, 毅
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Membrane Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023470/
https://ncbi.nlm.nih.gov/pubmed/21084291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171116
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