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An in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel

The bacterial mechanosensitive channel MscL is the best-studied mechanosensor, thus serving as a paradigm of how a protein senses and responds to mechanical force. Models for the transition of Escherichia coli MscL from closed to open states propose a tilting of the transmembrane domains in the plan...

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Autori principali: Iscla, Irene, Wray, Robin, Blount, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023395/
https://ncbi.nlm.nih.gov/pubmed/21068398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-170878
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