Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

Cardiac dysfunction is a common cause of death among pediatric patients with mutations in the lysosomal hydrolase α-l-iduronidase (IDUA) gene, which causes mucopolysaccharidosis type I (MPS-I). The purpose of this study was to analyze adrenergic regulation of cardiac hemodynamic function in MPS-I. A...

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Autores principales: Palpant, Nathan J., Bedada, Fikru B., Peacock, Brandon, Blazar, Bruce R., Metzger, Joseph M., Tolar, Jakub
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
Materias:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023247/
https://ncbi.nlm.nih.gov/pubmed/21076027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00774.2010
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