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Oxidative stress alters renal D1 and AT1 receptor functions and increases blood pressure in old rats

Aging is associated with an increase in oxidative stress and blood pressure (BP). Renal dopamine D1 (D1R) and angiotensin II AT1 (AT1R) receptors maintain sodium homeostasis and BP. We hypothesized that age-associated increase in oxidative stress causes altered D1R and AT1R functions and high BP in...

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Detalhes bibliográficos
Main Authors: Chugh, Gaurav, Lokhandwala, Mustafa F., Asghar, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023225/
https://ncbi.nlm.nih.gov/pubmed/20943769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00465.2010
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