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Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

Type 2 diabetes (T2DM) is characterized by hyperglycemia, dyslipidemia, and increased inflammation. Previously, we showed that high glucose (HG) induces Toll-like receptor (TLR) expression, activity, and inflammation via NF-κB followed by cytokine release in vitro and in vivo. Here, we determined ho...

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Bibliographic Details
Main Authors: Dasu, Mohan R., Jialal, Ishwarlal
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023203/
https://ncbi.nlm.nih.gov/pubmed/20959532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00490.2010
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