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Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo

INTRODUCTION: Toll-like receptors play an important role in the innate immune system and are found to be crucial in severe diseases like sepsis, atherosclerosis, and arthritis. TLR2 and TLR4 expression is upregulated in the inflammatory diseases. Angiotensin II in addition to stimulating vasoconstri...

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Detalhes bibliográficos
Main Authors: Dasu, Mohan R., Riosvelasco, Andrea C., Jialal, Ishwarlal
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676176/
https://ncbi.nlm.nih.gov/pubmed/18495130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2008.04.010
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